ACMG ACT Sheets
The ACMG ACT Sheets
and their accompanying algorithms are a great resources for health care providers looking for information on genetic conditions (identified through newborn screening and beyond) to help inform clinical decision making. Developed by the National Coordinating Center for the Regional Genetic Service Collaboratives (NCC) and the American College of Medical Genetics and Genomics (ACMG
), ACMG ACT Sheets
are available on the ACMG websites. Given the rarity of many genetic conditions—ACT Sheets and algorithms are excellent refreshers on the conditions, diagnoses, and next steps for patients.
For each marker(s), there is 1) an ACTion (ACT) sheet that describes the short term actions a health professional should follow in communicating with the family and determining the appropriate steps in the follow-up of the infant that has screened positive, and 2) an algorithm that presents an overview of the basic steps involved in determining the final diagnosis in the infant.
The first page of the ACT sheets includes information are developed by the ACT Sheet Workgroup
. Each ACT Sheet also include links to informational resources to allow the health professional to obtain additional information, if needed. The second page of the ACT sheet includes links to web sites that allow one to identify sub-specialists for consultation and referral for the condition(s) described in the ACT Sheet. It is supplemented with links to your State Newborn Screening Program and is available for the inclusion of additional health professionals who may be consulted in your area.
All materials are continuously approved in a review process by the Board of Directors of the American College of Medical Genetics and Genomics (ACMG). As new conditions are introduced into newborn screening programs, additional materials are added. The project is partially funded through grant U22MC24100 from the Maternal and Child Health Bureau (MCHB) of the Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services.